Does crying really helps fight bacteria in the eyes ?
- dinesh madduri
- Jun 13, 2021
- 1 min read
We should know about tear film biochemistry and its composition to know how it protects from bacterial and viral infections .
Tear film consists of 3 layers ,includes

Outer most lipid layer, derived from Meibomian glands, glands of Ziess and glands of Moll

The middle layer and the main bulk of tear film which is secreted by lacrimal glands and accessory glands of Krause and Wolfring

Deepest layer which is secreted by conjunctival goblet cells, crypts of Henle, gland of Manz .
What is the composition and how tears protect from bacterial and viral infections?
chemical composition
Water
Major component, 98.2%
With salts dissolved Na+, K+, Cl-, HCO3-, Ca2+
Proteins
Un-stimulated tears protein concentration: 2gm/100ml
Stimulated tears protein concentration (Crying) : 0.3-0.7 gm/100ml
Protein composition is also important for a healthy ocular surface
Tears contain a large number of proteins, which are secreted by the orbital glands
Tears do not normally contain serum proteins, although these can enter the tears from leaky conjunctival blood vessels under pathological conditions
One of the most important functions of tear proteins is preventing bacterial and viral infections. The major tear proteins like lysozyme, secretory immunoglobulin (IgA), lactoferrin, lipocalin, and peroxidase are antibacterial and antiviral
others like aminoacids ,lipids ,metabolites like glucose, pyruvate, etc which are useful for metabolism.
Functions of tear film :
Form a smooth optical surface by filling irregularities of corneal epithelium
Keeps the cornea and conjunctiva moist
Serves as a lubricant for lids
Transfer air to the cornea
Prevent infections
Washes away debris and irritants
Provides pathway to WBC in case of injury
So even you cry or not tear film protects you from infections .
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